## TITLE('Enzyme Names')
## DESCRIPTION
## Select the statement that is TRUE or FALSE about enzyme names.
## ENDDESCRIPTION
## KEYWORDS('enzyme names','true/false','multiple choice')
## DBsubject('Biochemistry')
## DBchapter('')
## DBsection('')
## Date('2026-07-12')
## Author('Neil R. Voss')
## Institution('Roosevelt University')

DOCUMENT();

loadMacros(
  "PGstandard.pl",
  "PGML.pl",
  "PGchoicemacros.pl",
  "parserRadioButtons.pl",
  "PGcourse.pl",
);

TEXT(beginproblem());
$showPartialCorrectAnswers = 1;

#==========================================================
# AUTO-GENERATED GROUPS FROM YAML
#==========================================================

@true_groups = (
  [
    'galactosidase',
  ],
  [
    'hexokinase',
  ],
  [
    'lactase',
  ],
  [
    'sucrase',
  ],
  [
    'maltase',
  ],
  [
    'pyruvate decarboxylase',
  ],
  [
    'lactate dehydrogenase',
  ],
  [
    'glyceraldehyde-3-phosphate dehydrogenase (GAPDH)',
  ],
  [
    'α-amylase',
  ],
  [
    'adenylyl cyclase',
  ],
  [
    'phosphofructokinase',
  ],
  [
    'carbonic anhydrase',
  ],
  [
    'acetylcholinesterase',
  ],
  [
    'catalase',
  ],
  [
    'DNA polymerase',
  ],
);
@false_groups = (
  [
    'phospholipid',
    'fatty acids',
    'triacylglycerol',
    'triglyceride',
  ],
  [
    'testosterone',
    'estrogen',
    'cholesterol',
  ],
  [
    'manganese ions (Mn<sup>2+</sup>)',
    'magnesium ions (Mg<sup>2+</sup>)',
    'calcium ions (Ca<sup>2+</sup>)',
    'sodium ions (Na<sup>+</sup>)',
    'potassium ions, K<sup>+</sup>',
    'iron ions, Fe<sup>+2</sup>/Fe<sup>+3</sup>',
    'zinc ions, Zn<sup>2+</sup>',
    'copper ions, Cu<sup>2+</sup>',
    'chloride ions, Cl<sup>-</sup>',
  ],
  [
    'chitin',
    'cellulose',
    'glycogen',
    'amylopectin',
    'amylose',
    'glucose',
    'galactose',
    'fructose',
    'lactose',
    'sucrose',
    'maltose',
    'pyruvate',
  ],
  [
    'actin filaments',
    'microtubules',
    'intermediate filaments',
    'collagen',
    'albumin',
  ],
  [
    'coenzyme A',
    'coenzyme Q',
    'NADH',
    'NADPH',
    'FADH<sub>2</sub>',
  ],
  [
    'GTP',
    'ATP',
    'GDP',
    'ADP',
    'GMP',
    'AMP',
  ],
  [
    'water (H<sub>2</sub>O)',
    'oxygen (O<sub>2</sub>)',
    'carbon dioxide (CO<sub>2</sub>)',
  ],
  [
    'steroid',
  ],
);

#==========================================================
# GLOBAL SETTINGS
#==========================================================

$topic = 'enzyme names';
my $local_random = PGrandom->new();
$local_random->srand($problemSeed);
my @mode_choices = ("TRUE", "FALSE");
$mode = $mode_choices[$local_random->random(0, $#mode_choices, 1)];
$num_distractors = 4;
# Question text with TRUE override
$question_true = 'Enzymes are biological catalysts that speed up chemical reactions in living organisms.Which one of the following choices is most likely an enzyme?<br/>Hint: enzymes often have a distinct naming pattern that can help identify them.';
#==========================================================
# SELECT GROUP
#==========================================================

my (@selected_group, @opposite_groups);

if ($mode eq "TRUE") {
  $group_index      = $local_random->random(0, scalar(@true_groups)-1, 1);
  @selected_group   = @{ $true_groups[$group_index] };
  @opposite_groups  = @false_groups;
} else {
  $group_index      = $local_random->random(0, scalar(@false_groups)-1, 1);
  @selected_group   = @{ $false_groups[$group_index] };
  @opposite_groups  = @true_groups;
}

#==========================================================
# PICK CORRECT + DISTRACTORS
#==========================================================

my $correct_index = $local_random->random(0, $#selected_group, 1);
$correct = $selected_group[$correct_index];

my @available_group_indices = (0 .. $#opposite_groups);
my @selected_distractor_indices = ();

while (@selected_distractor_indices < $num_distractors && @available_group_indices > 0) {
  my $random_index = $local_random->random(0, scalar(@available_group_indices)-1, 1);
  push @selected_distractor_indices, splice(@available_group_indices, $random_index, 1);
}

@distractors = ();
foreach my $group_idx (@selected_distractor_indices) {
  my @group = @{ $opposite_groups[$group_idx] };
  my $distractor_index = $local_random->random(0, $#group, 1);
  my $distractor = $group[$distractor_index];
  push @distractors, $distractor;
}

@choices = ($correct, @distractors);

#==========================================================
# SHUFFLE CHOICES (SEED-STABLE)
#==========================================================

my @choice_indices = (0 .. $#choices);
my @choice_shuffled = ();
while (@choice_indices) {
  my $pick = $local_random->random(0, $#choice_indices, 1);
  push @choice_shuffled, splice(@choice_indices, $pick, 1);
}
@choices = @choices[@choice_shuffled];

#==========================================================
# RADIO BUTTONS WITH A/B/C/D/E LABELS
#==========================================================

$rb = RadioButtons(
  [@choices],
  $correct,
  labels        => ['A','B','C','D','E'],
  displayLabels => 1,
  randomize     => 0,
  separator     => '<div style="margin-bottom: 0.7em;"></div>',
);

#==========================================================
# PGML
#==========================================================

BEGIN_PGML

[@ $mode eq "TRUE" ? $question_true : "Which one of the following statements is <span style='color: #ba372a;'><strong>FALSE</strong></span> about $topic?" @]*

[_]{$rb}

END_PGML

ENDDOCUMENT();