MAT

5f6d_feb9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cGMP Second messenger that keeps rod CNG channels open in the dark Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_c615

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Gustducin G protein that couples taste GPCRs to downstream second messengers Golf Heterotrimeric G protein used in olfactory GPCR pathways Transducin Heterotrimeric G protein in the visual cascade Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_7786

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Transducin G protein that activates PDE6 in rod phototransduction Gustducin Heterotrimeric G protein in taste receptor signaling cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_97fe

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Cyclic nucleotide that gates rod outer segment ion channels CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Transducin Rod G protein linking rhodopsin to cGMP breakdown Gustducin Taste G protein used in bitter and sweet pathways Rhodopsin Light-activated GPCR in rod photoreceptors TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger MAT

5f6d_6fba

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_e216

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling TRPM5 Ion channel involved in taste transduction downstream of IP3 Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs IP3 Second messenger that triggers Ca2+ release from ER stores Rhodopsin Photopigment that starts rod phototransduction Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_6d97

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cGMP Cyclic nucleotide that gates rod outer segment ion channels MAT

5f6d_e6d1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_427c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells IP3 Second messenger that triggers Ca2+ release from ER stores Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin Heterotrimeric G protein in the visual cascade Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_fa2c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling cGMP Signaling nucleotide that falls in light, closing CNG channels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Golf G protein coupling olfactory receptors to cAMP signaling IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_cc4e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_9526

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production TRPM5 Ion channel involved in taste transduction downstream of IP3 MAT

5f6d_0a81

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Gustducin Heterotrimeric G protein in taste receptor signaling Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation IP3 Second messenger that triggers Ca2+ release from ER stores cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_3efd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Rhodopsin Light-activated GPCR in rod photoreceptors Gustducin Taste G protein used in bitter and sweet pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_bf21

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin Heterotrimeric G protein in taste receptor signaling Transducin Heterotrimeric G protein in the visual cascade cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_9ded

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cGMP Second messenger that keeps rod CNG channels open in the dark Transducin G protein that activates PDE6 in rod phototransduction Rhodopsin Photopigment that starts rod phototransduction Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_a04a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Transducin Heterotrimeric G protein in the visual cascade Rhodopsin Light-activated GPCR in rod photoreceptors IP3 Second messenger that triggers Ca2+ release from ER stores Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_9850

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Transducin Rod G protein linking rhodopsin to cGMP breakdown Rhodopsin Light-activated GPCR in rod photoreceptors TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Golf Heterotrimeric G protein used in olfactory GPCR pathways Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_99da

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Golf Heterotrimeric G protein used in olfactory GPCR pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_2ffd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Golf G protein coupling olfactory receptors to cAMP signaling cGMP Signaling nucleotide that falls in light, closing CNG channels CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Photopigment that starts rod phototransduction Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_c5c1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Second messenger made from ATP that rises during odor detection Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_34f3

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_ccc9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (rod outer segment) Rod channel controlled by cGMP levels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin cGMP Second messenger that keeps rod CNG channels open in the dark IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Gustducin G protein that couples taste GPCRs to downstream second messengers Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_4c3f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Gustducin Taste G protein used in bitter and sweet pathways Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Golf G protein coupling olfactory receptors to cAMP signaling Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_f67a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Second messenger made from ATP that rises during odor detection Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_196b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways cGMP Second messenger that keeps rod CNG channels open in the dark Rhodopsin Light-activated GPCR in rod photoreceptors CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Transducin Rod G protein linking rhodopsin to cGMP breakdown Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_9961

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Transducin G protein that activates PDE6 in rod phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Photopigment that starts rod phototransduction cAMP Second messenger made from ATP that rises during odor detection MAT

5f6d_95e0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Gustducin Taste G protein used in bitter and sweet pathways CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Ion channel involved in taste transduction downstream of IP3 Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_fb6d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection cGMP Cyclic nucleotide that gates rod outer segment ion channels Golf Olfactory G protein that activates adenylyl cyclase TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_a2e0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Gustducin G protein that couples taste GPCRs to downstream second messengers Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Second messenger that triggers Ca2+ release from ER stores Transducin Rod G protein linking rhodopsin to cGMP breakdown CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_3a25

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Gustducin Taste G protein used in bitter and sweet pathways Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_fab2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin Taste G protein used in bitter and sweet pathways Transducin G protein that activates PDE6 in rod phototransduction CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_e8e7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_ef90

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Golf Heterotrimeric G protein used in olfactory GPCR pathways Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons cAMP Signaling molecule that helps open olfactory CNG channels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_c79d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction cAMP Signaling molecule that helps open olfactory CNG channels Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_4d6f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Signaling molecule that helps open olfactory CNG channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_03f1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Gustducin Taste G protein used in bitter and sweet pathways Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cGMP Second messenger that keeps rod CNG channels open in the dark Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_bb72

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cAMP Second messenger made from ATP that rises during odor detection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_dfc9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels cGMP Second messenger that keeps rod CNG channels open in the dark Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Transducin G protein that activates PDE6 in rod phototransduction CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_9dfe

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Signaling nucleotide that falls in light, closing CNG channels Golf G protein coupling olfactory receptors to cAMP signaling Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Gustducin Taste G protein used in bitter and sweet pathways CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_6d2b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Rhodopsin Photopigment that starts rod phototransduction CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf G protein coupling olfactory receptors to cAMP signaling Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_2b14

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Transducin Rod G protein linking rhodopsin to cGMP breakdown Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons cGMP Cyclic nucleotide that gates rod outer segment ion channels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Gustducin Heterotrimeric G protein in taste receptor signaling Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 MAT

5f6d_18c8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Photopigment that starts rod phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Golf Olfactory G protein that activates adenylyl cyclase Transducin G protein that activates PDE6 in rod phototransduction cGMP Signaling nucleotide that falls in light, closing CNG channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_f2b2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin cAMP Signaling molecule that helps open olfactory CNG channels Transducin G protein that activates PDE6 in rod phototransduction Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_5db5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Transducin G protein that activates PDE6 in rod phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Golf Heterotrimeric G protein used in olfactory GPCR pathways Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_fa0b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Transducin Heterotrimeric G protein in the visual cascade Golf Heterotrimeric G protein used in olfactory GPCR pathways Rhodopsin Photopigment that starts rod phototransduction Gustducin Taste G protein used in bitter and sweet pathways cAMP Second messenger made from ATP that rises during odor detection MAT

5f6d_d6d8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Signaling molecule that helps open olfactory CNG channels Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown Gustducin G protein that couples taste GPCRs to downstream second messengers IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_5646

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Rod channel controlled by cGMP levels Rhodopsin Photopigment that starts rod phototransduction Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Golf Heterotrimeric G protein used in olfactory GPCR pathways TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_858f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Gustducin G protein that couples taste GPCRs to downstream second messengers cGMP Cyclic nucleotide that gates rod outer segment ion channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Transducin Rod G protein linking rhodopsin to cGMP breakdown Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_f16f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Second messenger made from ATP that rises during odor detection Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_78b4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Golf Heterotrimeric G protein used in olfactory GPCR pathways TRPM5 Ion channel involved in taste transduction downstream of IP3 MAT

5f6d_9944

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Transducin Rod G protein linking rhodopsin to cGMP breakdown Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_870f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Signaling molecule that helps open olfactory CNG channels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Gustducin Heterotrimeric G protein in taste receptor signaling Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_3e8a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation cGMP Second messenger that keeps rod CNG channels open in the dark TRPM5 Ion channel involved in taste transduction downstream of IP3 Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Rhodopsin Photopigment that starts rod phototransduction Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_c9b8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction cGMP Signaling nucleotide that falls in light, closing CNG channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_5cdf

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Rhodopsin Light-activated GPCR in rod photoreceptors Golf G protein coupling olfactory receptors to cAMP signaling cGMP Second messenger that keeps rod CNG channels open in the dark Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins TRPM5 Ion channel involved in taste transduction downstream of IP3 MAT

5f6d_d60d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_b40e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Rhodopsin Light-activated GPCR in rod photoreceptors TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Gustducin Taste G protein used in bitter and sweet pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Golf Heterotrimeric G protein used in olfactory GPCR pathways MAT

5f6d_ec3e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Photopigment that starts rod phototransduction Transducin Heterotrimeric G protein in the visual cascade cAMP Second messenger made from ATP that rises during odor detection Gustducin Heterotrimeric G protein in taste receptor signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_7802

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection TRPM5 Ion channel involved in taste transduction downstream of IP3 Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Olfactory G protein that activates adenylyl cyclase CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_406a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance cAMP Signaling molecule that helps open olfactory CNG channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_fc53

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Rod G protein linking rhodopsin to cGMP breakdown IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin G protein that couples taste GPCRs to downstream second messengers cAMP Signaling molecule that helps open olfactory CNG channels CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_cb19

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction Transducin G protein that activates PDE6 in rod phototransduction cGMP Cyclic nucleotide that gates rod outer segment ion channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin Heterotrimeric G protein in taste receptor signaling Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) Rod channel controlled by cGMP levels MAT

5f6d_330f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores cAMP Second messenger made from ATP that rises during odor detection Gustducin G protein that couples taste GPCRs to downstream second messengers Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_525c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation CNG channel (rod outer segment) Rod channel controlled by cGMP levels Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 MAT

5f6d_2d9c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf G protein coupling olfactory receptors to cAMP signaling CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_dc6b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin Heterotrimeric G protein in taste receptor signaling cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_2e87

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Olfactory G protein that activates adenylyl cyclase Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells TRPM5 Ion channel involved in taste transduction downstream of IP3 Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_662f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_1e35

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_3981

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Gustducin G protein that couples taste GPCRs to downstream second messengers Transducin G protein that activates PDE6 in rod phototransduction Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_ecde

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase Gustducin Heterotrimeric G protein in taste receptor signaling Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_e6f7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin cGMP Signaling nucleotide that falls in light, closing CNG channels MAT

5f6d_a20a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Rhodopsin Photopigment that starts rod phototransduction Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_63ea

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Transducin Rod G protein linking rhodopsin to cGMP breakdown Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_e8b7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Rhodopsin Light-activated GPCR in rod photoreceptors cAMP Cytosolic second messenger produced downstream of olfactory GPCRs CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger MAT

5f6d_29f9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Rod channel controlled by cGMP levels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_ec9d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance cAMP Signaling molecule that helps open olfactory CNG channels Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin G protein that activates PDE6 in rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_4dd7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin G protein that couples taste GPCRs to downstream second messengers Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation MAT

5f6d_3d13

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Rod channel controlled by cGMP levels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Golf Heterotrimeric G protein used in olfactory GPCR pathways Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_0569

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cAMP Signaling molecule that helps open olfactory CNG channels Gustducin G protein that couples taste GPCRs to downstream second messengers Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_89c2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Gustducin Heterotrimeric G protein in taste receptor signaling Golf G protein coupling olfactory receptors to cAMP signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling TRPM5 Ion channel involved in taste transduction downstream of IP3 MAT

5f6d_743a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction cGMP Second messenger that keeps rod CNG channels open in the dark Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Transducin Heterotrimeric G protein in the visual cascade MAT

5f6d_ea45

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Second messenger that triggers Ca2+ release from ER stores Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Golf G protein coupling olfactory receptors to cAMP signaling cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_2b00

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cGMP Cyclic nucleotide that gates rod outer segment ion channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_ce70

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin G protein that activates PDE6 in rod phototransduction Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Gustducin Taste G protein used in bitter and sweet pathways Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_90b0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_c477

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Gustducin Heterotrimeric G protein in taste receptor signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf G protein coupling olfactory receptors to cAMP signaling cGMP Signaling nucleotide that falls in light, closing CNG channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_31c7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cGMP Second messenger that keeps rod CNG channels open in the dark Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_7a79

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cGMP Signaling nucleotide that falls in light, closing CNG channels Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_ebee

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Rhodopsin Light-activated GPCR in rod photoreceptors cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_1eda

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade IP3 Second messenger that triggers Ca2+ release from ER stores Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Gustducin G protein that couples taste GPCRs to downstream second messengers Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_5d6d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cAMP Signaling molecule that helps open olfactory CNG channels Rhodopsin Light-activated GPCR in rod photoreceptors TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_6ef0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Rhodopsin Light-activated GPCR in rod photoreceptors Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_2c62

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Rhodopsin Photopigment that starts rod phototransduction Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_ad7a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Gustducin G protein that couples taste GPCRs to downstream second messengers cAMP Signaling molecule that helps open olfactory CNG channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells CNG channel (rod outer segment) Rod channel controlled by cGMP levels Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_7987

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin G protein that activates PDE6 in rod phototransduction IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_4d08

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin Rod G protein linking rhodopsin to cGMP breakdown Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons MAT

5f6d_b420

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_fef4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Golf G protein coupling olfactory receptors to cAMP signaling CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection TRPM5 Ion channel involved in taste transduction downstream of IP3 Transducin Heterotrimeric G protein in the visual cascade Gustducin Heterotrimeric G protein in taste receptor signaling Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_6851

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Golf Olfactory G protein that activates adenylyl cyclase CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_4869

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection CNG channel (rod outer segment) Rod channel controlled by cGMP levels Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cGMP Signaling nucleotide that falls in light, closing CNG channels Transducin G protein that activates PDE6 in rod phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_0a2d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin Taste G protein used in bitter and sweet pathways Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Light-activated GPCR in rod photoreceptors Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light MAT

5f6d_a862

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin Heterotrimeric G protein in the visual cascade CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_d73e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin Rod G protein linking rhodopsin to cGMP breakdown Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cAMP Second messenger made from ATP that rises during odor detection MAT

5f6d_10b9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_ec99

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Gustducin G protein that couples taste GPCRs to downstream second messengers TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Golf Olfactory G protein that activates adenylyl cyclase CNG channel (rod outer segment) Rod channel controlled by cGMP levels MAT

5f6d_c211

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Transducin G protein that activates PDE6 in rod phototransduction Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Golf Heterotrimeric G protein used in olfactory GPCR pathways MAT

5f6d_b639

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_91e9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection CNG channel (rod outer segment) Rod channel controlled by cGMP levels cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_6a1a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels IP3 Second messenger that triggers Ca2+ release from ER stores Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Gustducin Taste G protein used in bitter and sweet pathways Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cGMP Signaling nucleotide that falls in light, closing CNG channels MAT

5f6d_1dd5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_7904

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels CNG channel (rod outer segment) Rod channel controlled by cGMP levels MAT

5f6d_d324

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cAMP Cytosolic second messenger produced downstream of olfactory GPCRs TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_be6b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Golf Heterotrimeric G protein used in olfactory GPCR pathways Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Transducin G protein that activates PDE6 in rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_e0fa

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Golf G protein coupling olfactory receptors to cAMP signaling Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_f3b8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_6ffe

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Second messenger that triggers Ca2+ release from ER stores cAMP Second messenger made from ATP that rises during odor detection CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_b63d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_5f6e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Second messenger that triggers Ca2+ release from ER stores cAMP Signaling molecule that helps open olfactory CNG channels Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin G protein that activates PDE6 in rod phototransduction Golf Olfactory G protein that activates adenylyl cyclase Gustducin G protein that couples taste GPCRs to downstream second messengers Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_33e8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Golf G protein coupling olfactory receptors to cAMP signaling Gustducin Taste G protein used in bitter and sweet pathways cGMP Second messenger that keeps rod CNG channels open in the dark Rhodopsin Photopigment that starts rod phototransduction IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_2785

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin Heterotrimeric G protein in the visual cascade Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Ion channel involved in taste transduction downstream of IP3 Golf Heterotrimeric G protein used in olfactory GPCR pathways Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_af19

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Golf Olfactory G protein that activates adenylyl cyclase Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Rod channel controlled by cGMP levels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_1450

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways cAMP Second messenger made from ATP that rises during odor detection Gustducin Taste G protein used in bitter and sweet pathways Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_85bf

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation cGMP Cyclic nucleotide that gates rod outer segment ion channels CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Rhodopsin Light-activated GPCR in rod photoreceptors TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_1b1f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Golf Olfactory G protein that activates adenylyl cyclase CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons cAMP Cytosolic second messenger produced downstream of olfactory GPCRs IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_4e2c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons MAT

5f6d_5327

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Golf G protein coupling olfactory receptors to cAMP signaling Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_1099

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Transducin Heterotrimeric G protein in the visual cascade Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_c346

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Cyclic nucleotide that gates rod outer segment ion channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_e41c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Transducin G protein that activates PDE6 in rod phototransduction cGMP Second messenger that keeps rod CNG channels open in the dark Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_5166

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown Gustducin Taste G protein used in bitter and sweet pathways cGMP Cyclic nucleotide that gates rod outer segment ion channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_0bcc

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons cAMP Second messenger made from ATP that rises during odor detection Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Golf Olfactory G protein that activates adenylyl cyclase Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_d86c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_a9b7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Signaling molecule that helps open olfactory CNG channels Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_043a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger cGMP Cyclic nucleotide that gates rod outer segment ion channels IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_0c50

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Gustducin G protein that couples taste GPCRs to downstream second messengers Golf Heterotrimeric G protein used in olfactory GPCR pathways cAMP Signaling molecule that helps open olfactory CNG channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_7108

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Molecule that opens IP3 receptors on internal Ca2+ stores cGMP Cyclic nucleotide that gates rod outer segment ion channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_7b62

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance IP3 Second messenger that triggers Ca2+ release from ER stores Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons cGMP Signaling nucleotide that falls in light, closing CNG channels Transducin Heterotrimeric G protein in the visual cascade Gustducin G protein that couples taste GPCRs to downstream second messengers Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_e917

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Second messenger that triggers Ca2+ release from ER stores Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_2811

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cAMP Cytosolic second messenger produced downstream of olfactory GPCRs CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_7484

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Gustducin Taste G protein used in bitter and sweet pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_3c93

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation cGMP Cyclic nucleotide that gates rod outer segment ion channels MAT

5f6d_7c47

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Golf Heterotrimeric G protein used in olfactory GPCR pathways Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Gustducin G protein that couples taste GPCRs to downstream second messengers Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_0e68

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Second messenger that triggers Ca2+ release from ER stores Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins cGMP Signaling nucleotide that falls in light, closing CNG channels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_d2c3

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Second messenger that keeps rod CNG channels open in the dark Golf Olfactory G protein that activates adenylyl cyclase Gustducin Taste G protein used in bitter and sweet pathways Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_e6ed

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin Rod G protein linking rhodopsin to cGMP breakdown TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Heterotrimeric G protein used in olfactory GPCR pathways Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_aa11

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin G protein that activates PDE6 in rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin G protein that couples taste GPCRs to downstream second messengers TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Rhodopsin Photopigment that starts rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_3004

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (rod outer segment) Rod channel controlled by cGMP levels Gustducin Heterotrimeric G protein in taste receptor signaling Golf Heterotrimeric G protein used in olfactory GPCR pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_0fb8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Golf Olfactory G protein that activates adenylyl cyclase Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_ba68

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Light-activated GPCR in rod photoreceptors cAMP Second messenger made from ATP that rises during odor detection Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Gustducin Heterotrimeric G protein in taste receptor signaling TRPM5 Ion channel involved in taste transduction downstream of IP3 IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_8b79

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers IP3 Molecule that opens IP3 receptors on internal Ca2+ stores cGMP Cyclic nucleotide that gates rod outer segment ion channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_225d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Rhodopsin Photopigment that starts rod phototransduction CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance cGMP Second messenger that keeps rod CNG channels open in the dark Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_28c9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Olfactory G protein that activates adenylyl cyclase cAMP Signaling molecule that helps open olfactory CNG channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_38ac

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Golf Olfactory G protein that activates adenylyl cyclase Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation MAT

5f6d_12e5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Signaling nucleotide that falls in light, closing CNG channels Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light TRPM5 Ion channel involved in taste transduction downstream of IP3 Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_817d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Rhodopsin Photopigment that starts rod phototransduction CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection IP3 Second messenger that triggers Ca2+ release from ER stores Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_1ed8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Gustducin Taste G protein used in bitter and sweet pathways CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf G protein coupling olfactory receptors to cAMP signaling TRPM5 Ion channel involved in taste transduction downstream of IP3 cGMP Signaling nucleotide that falls in light, closing CNG channels MAT

5f6d_e027

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Rhodopsin Light-activated GPCR in rod photoreceptors IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_ce67

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Gustducin Taste G protein used in bitter and sweet pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels MAT

5f6d_22f0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores TRPM5 Ion channel involved in taste transduction downstream of IP3 Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light cGMP Cyclic nucleotide that gates rod outer segment ion channels Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_a921

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Second messenger that triggers Ca2+ release from ER stores cAMP Cytosolic second messenger produced downstream of olfactory GPCRs TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (rod outer segment) Rod channel controlled by cGMP levels Rhodopsin Light-activated GPCR in rod photoreceptors Gustducin Taste G protein used in bitter and sweet pathways Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_9c1f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Gustducin Taste G protein used in bitter and sweet pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response cAMP Signaling molecule that helps open olfactory CNG channels MAT

5f6d_00e9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Transducin Rod G protein linking rhodopsin to cGMP breakdown Rhodopsin Photopigment that starts rod phototransduction Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_ec58

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light cGMP Second messenger that keeps rod CNG channels open in the dark Transducin Rod G protein linking rhodopsin to cGMP breakdown Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Olfactory G protein that activates adenylyl cyclase IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_a27b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Transducin G protein that activates PDE6 in rod phototransduction Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cGMP Signaling nucleotide that falls in light, closing CNG channels IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_0f54

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels CNG channel (rod outer segment) Rod channel controlled by cGMP levels Gustducin Heterotrimeric G protein in taste receptor signaling Transducin Heterotrimeric G protein in the visual cascade IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_7f7e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Rhodopsin Light-activated GPCR in rod photoreceptors IP3 Second messenger that triggers Ca2+ release from ER stores TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (rod outer segment) Rod channel controlled by cGMP levels cAMP Second messenger made from ATP that rises during odor detection Golf Olfactory G protein that activates adenylyl cyclase Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_c603

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cGMP Cyclic nucleotide that gates rod outer segment ion channels Transducin G protein that activates PDE6 in rod phototransduction Rhodopsin Photopigment that starts rod phototransduction CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf Heterotrimeric G protein used in olfactory GPCR pathways Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_24cd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin Heterotrimeric G protein in taste receptor signaling Transducin G protein that activates PDE6 in rod phototransduction CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Golf G protein coupling olfactory receptors to cAMP signaling Rhodopsin Photopigment that starts rod phototransduction Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_8ed3

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_2fa6

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Transducin Heterotrimeric G protein in the visual cascade Gustducin Heterotrimeric G protein in taste receptor signaling Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_93f9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Golf Olfactory G protein that activates adenylyl cyclase cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Rhodopsin Photopigment that starts rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_6335

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf Olfactory G protein that activates adenylyl cyclase Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels cGMP Signaling nucleotide that falls in light, closing CNG channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Ion channel involved in taste transduction downstream of IP3 MAT

5f6d_8b7f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins cGMP Second messenger that keeps rod CNG channels open in the dark Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Golf G protein coupling olfactory receptors to cAMP signaling Transducin Heterotrimeric G protein in the visual cascade CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_d78a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Cyclic nucleotide that gates rod outer segment ion channels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Gustducin G protein that couples taste GPCRs to downstream second messengers Golf G protein coupling olfactory receptors to cAMP signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 MAT

5f6d_4ce5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin Taste G protein used in bitter and sweet pathways cGMP Cyclic nucleotide that gates rod outer segment ion channels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin G protein that activates PDE6 in rod phototransduction Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_7212

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin Heterotrimeric G protein in the visual cascade Gustducin Taste G protein used in bitter and sweet pathways Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_2027

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Rod G protein linking rhodopsin to cGMP breakdown Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cAMP Second messenger made from ATP that rises during odor detection Rhodopsin Light-activated GPCR in rod photoreceptors Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_c0ee

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_6f1f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Golf G protein coupling olfactory receptors to cAMP signaling Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling TRPM5 Ion channel involved in taste transduction downstream of IP3 cGMP Second messenger that keeps rod CNG channels open in the dark MAT

5f6d_c68f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Light-activated GPCR in rod photoreceptors Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Gustducin Heterotrimeric G protein in taste receptor signaling Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_7ec7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin G protein that activates PDE6 in rod phototransduction Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins cAMP Second messenger made from ATP that rises during odor detection Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod MAT

5f6d_5af8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Second messenger that keeps rod CNG channels open in the dark Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Gustducin Heterotrimeric G protein in taste receptor signaling Rhodopsin Light-activated GPCR in rod photoreceptors IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_a1c5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Transducin G protein that activates PDE6 in rod phototransduction TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cAMP Signaling molecule that helps open olfactory CNG channels Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_d69e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Gustducin Taste G protein used in bitter and sweet pathways Transducin Heterotrimeric G protein in the visual cascade Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cGMP Second messenger that keeps rod CNG channels open in the dark MAT

5f6d_2442

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction Golf Olfactory G protein that activates adenylyl cyclase IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins TRPM5 Ion channel involved in taste transduction downstream of IP3 Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_6ab8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Gustducin Taste G protein used in bitter and sweet pathways TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_7f11

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin Rod G protein linking rhodopsin to cGMP breakdown Rhodopsin Photopigment that starts rod phototransduction Gustducin Taste G protein used in bitter and sweet pathways Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Golf Heterotrimeric G protein used in olfactory GPCR pathways cGMP Second messenger that keeps rod CNG channels open in the dark Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels MAT

5f6d_0e93

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Second messenger made from ATP that rises during odor detection Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Golf G protein coupling olfactory receptors to cAMP signaling Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light MAT

5f6d_3ccf

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Golf Olfactory G protein that activates adenylyl cyclase TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_8a29

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Gustducin Taste G protein used in bitter and sweet pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_2b81

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_d94b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cGMP Signaling nucleotide that falls in light, closing CNG channels Golf Heterotrimeric G protein used in olfactory GPCR pathways MAT

5f6d_1ac4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light IP3 Second messenger that triggers Ca2+ release from ER stores Transducin G protein that activates PDE6 in rod phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_a7de

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Gustducin Heterotrimeric G protein in taste receptor signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Second messenger made from ATP that rises during odor detection MAT

5f6d_848e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling Gustducin Heterotrimeric G protein in taste receptor signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs IP3 Second messenger that triggers Ca2+ release from ER stores cAMP Signaling molecule that helps open olfactory CNG channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_ff92

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Transducin Rod G protein linking rhodopsin to cGMP breakdown Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels TRPM5 Ion channel involved in taste transduction downstream of IP3 Gustducin Heterotrimeric G protein in taste receptor signaling CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_c50e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores Golf Heterotrimeric G protein used in olfactory GPCR pathways Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cAMP Second messenger made from ATP that rises during odor detection TRPM5 Ion channel involved in taste transduction downstream of IP3 CNG channel (rod outer segment) Rod channel controlled by cGMP levels