e24f_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC383a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6ffb_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC110b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCec6a_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both AIS and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: AIS is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both AIS and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCe3e6_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6dde_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both AIS and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: AIS is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both AIS and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCc52e_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: DMD is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC9ac3_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC8024_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCc156_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC49d4_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCc9d5_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC110b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC004e_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC7277_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both AIS and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: AIS is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC51b4_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC7ba4_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCdbd8_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: AIS is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both AIS and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCfb6b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC51b4_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCcb1e_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC003a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC003a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC003a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC260d_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC110b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC605a_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCbb56_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCede3_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC51b4_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC4ac9_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: AIS is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCfb6b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC69f5_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC9ac3_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6db7_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC2abf_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: DMD is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC383a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC7277_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both AIS and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: AIS is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCc52e_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: DMD is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC110b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC24db_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC69f5_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6ffb_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC4b7b_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC49d4_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC004e_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC383a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC24db_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC49d4_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC49d4_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC605a_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCe3e6_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC51b4_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC5c1d_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC24db_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCcb1e_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCc156_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC004e_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC7ce7_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: DMD is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both DMD and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6db7_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC605a_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC4b7b_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCb751_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCd129_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC9ac3_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC713f_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC4ac9_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: AIS is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC003a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC713f_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC8024_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCcb1e_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6ffb_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCec6a_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both AIS and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: AIS is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both AIS and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCb751_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCede3_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: color blindness is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC24db_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC4b7b_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: DMD is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCc9d5_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC004e_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCdbd8_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: AIS is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both AIS and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC110b_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: HemA is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both HemA and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC8224_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC260d_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC0f2f_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: DMD is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both DMD and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC004e_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC004e_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC2abf_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both DMD and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: DMD is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC383a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC7ba4_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both HemA and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: HemA is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both HemA and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC8024_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both color blindness and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: color blindness is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both color blindness and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCd129_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCcb1e_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC6ffb_e69f
Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder that is caused by mutations in the DMD gene. This results in dystrophin is responsible for connecting the actin cytoskeleton to the extracellular matrix (ECM) in muscle cells. The disorder affects 1 in 20,000 males. Individuals affected with DMD have muscle weakness, trouble standing up, which eventually leads to loss of skeletal muscle control, respiratory failure, and death. The defective gene for DMD is located on the short arm of chromosome X at position 21.2.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both DMD and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the DMD genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: DMD is X-linked recessive and MFS is autosomal dominant.
What fraction of their daughters (♀) will have both DMD and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCcb1e_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both AIS and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: AIS is X-linked recessive and HD is autosomal dominant.
What fraction of their daughters (♀) will have both AIS and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCd129_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCe24f_e69f
Hemophilia A (HemA) is an X-linked recessive genetic disorder that is caused by a mutation in the HEMA gene. This results in blood cannot clot properly due to a deficiency of a clotting factor. The disorder affects 1 in 1,000 American males. Individuals affected with HemA have prolonged bleeding from common injuries. The defective gene for HemA is located on the long arm of chromosome X at position 28.
Huntington's disease (HD) is an autosomal dominant genetic disorder that is caused by an increase in trinucleotide repeats in the HTT gene. This results in a mutated Huntington protein that is toxic to certain cell types, particularly brain cells. The disorder affects 1 in 10,000 adults of European descent. Individuals affected with HD have physical abilities that gradually worsen and mental abilities that decline into dementia. The defective gene for HD is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both HemA and HD genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the HemA genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the HD genetic disorder.
Reminder: HemA is X-linked recessive and HD is autosomal dominant.
What fraction of their sons (♂) will have both HemA and HD genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MC383a_e69f
Deuteranomaly red-green color blindness is an X-linked recessive genetic disorder that is caused by mutations in the OPN1MW gene. This results in shift in the green retinal receptors toward red wavelength sensitivity. The disorder affects 1 in 20 males and 1 in 400 females of Northern European ancestry. Individuals affected with color blindness have decreased ability to see colors in which they are unable distinguish between shades of red and green. The defective gene for color blindness is located on the long arm of chromosome X at position 28.
Achondroplasia is an autosomal dominant genetic disorder that is caused by a mutation in the FGFR3 gene. This results in a mutated protein that interacts negatively with growth factors leading to complications with bone production. The disorder affects 1 in 27,500 people. Individuals affected with achondroplasia have dwarfism with short arms and legs, an enlarged head, and a prominent forehead. The defective gene for achondroplasia is located on the short arm of chromosome 4 at position 16.3.
A man (♂) with both color blindness and achondroplasia genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the color blindness genetic disorder,but mother (♀) of the woman does not. The mother (♀) of the man is wild-type phenotype and does not have the achondroplasia genetic disorder.
Reminder: color blindness is X-linked recessive and achondroplasia is autosomal dominant.
What fraction of their sons (♂) will have both color blindness and achondroplasia genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect MCec6a_e69f
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disorder that is caused by a mutation in the AR gene for the human androgen receptor. This results in partial or complete inability of cells to respond to androgens. The disorder affects 1 in 20,000. Individuals affected with AIS have impaired development of male genitals and male secondary sexual characteristics at puberty. The defective gene for AIS is located on the long arm of chromosome X at position 11.
Marfan syndrome (MFS) is an autosomal dominant genetic disorder that is caused by a mutation in FBN1 gene that makes fibrillin protein. This results in weaked connective tissue throughout the body. The disorder affects 1 in 10,000 people. Individuals affected with MFS have tall and thin features with serious complications involving the heart and aorta. The defective gene for MFS is located on the long arm of chromosome 15 at position 21.1.
A man (♂) with both AIS and MFS genetic disorders marries a wild-type phenotype woman (♀) with neither disorder. The father (♂) of the woman has the AIS genetic disorder,but mother (♀) of the woman does not. The father (♂) of the man is wild-type phenotype and does not have the MFS genetic disorder.
Reminder: AIS is X-linked recessive and MFS is autosomal dominant.
What fraction of their sons (♂) will have both AIS and MFS genetic disorders?
A. None, 0% Incorrect B. 1/4, 25% Correct C. 1/2, 50% Incorrect D. 3/4, 75% Incorrect E. All, 100% Incorrect