MAT

5f6d_5dfc

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Gustducin Taste G protein used in bitter and sweet pathways IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_a56f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation cGMP Cyclic nucleotide that gates rod outer segment ion channels IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells CNG channel (rod outer segment) Rod channel controlled by cGMP levels Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_e32c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Gustducin Taste G protein used in bitter and sweet pathways Golf G protein coupling olfactory receptors to cAMP signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown cGMP Cyclic nucleotide that gates rod outer segment ion channels Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_ef20

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cAMP Signaling molecule that helps open olfactory CNG channels Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_2097

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf Heterotrimeric G protein used in olfactory GPCR pathways Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_75ed

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cAMP Second messenger made from ATP that rises during odor detection Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Golf Olfactory G protein that activates adenylyl cyclase IP3 Second messenger that triggers Ca2+ release from ER stores Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_f1e2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cGMP Cyclic nucleotide that gates rod outer segment ion channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Transducin Rod G protein linking rhodopsin to cGMP breakdown Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_c632

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Golf Heterotrimeric G protein used in olfactory GPCR pathways Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_087b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction cGMP Second messenger that keeps rod CNG channels open in the dark Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling TRPM5 Ion channel involved in taste transduction downstream of IP3 Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_de8f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Gustducin G protein that couples taste GPCRs to downstream second messengers Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Transducin G protein that activates PDE6 in rod phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_63f6

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Second messenger that triggers Ca2+ release from ER stores TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_b249

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Rhodopsin Light-activated GPCR in rod photoreceptors cAMP Signaling molecule that helps open olfactory CNG channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_ae66

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Photopigment that starts rod phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_bab7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Transducin G protein that activates PDE6 in rod phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation MAT

5f6d_e4ad

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin Taste G protein used in bitter and sweet pathways CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Golf Olfactory G protein that activates adenylyl cyclase TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_e5fb

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels MAT

5f6d_0bff

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Rhodopsin Photopigment that starts rod phototransduction Transducin G protein that activates PDE6 in rod phototransduction cGMP Signaling nucleotide that falls in light, closing CNG channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation CNG channel (rod outer segment) Rod channel controlled by cGMP levels MAT

5f6d_91a1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Gustducin Heterotrimeric G protein in taste receptor signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Cytosolic second messenger produced downstream of olfactory GPCRs CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_54d6

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance IP3 Second messenger that triggers Ca2+ release from ER stores cGMP Cyclic nucleotide that gates rod outer segment ion channels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Transducin Heterotrimeric G protein in the visual cascade Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Golf Heterotrimeric G protein used in olfactory GPCR pathways MAT

5f6d_80a4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (rod outer segment) Rod channel controlled by cGMP levels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_feb5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Second messenger made from ATP that rises during odor detection Gustducin G protein that couples taste GPCRs to downstream second messengers Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger MAT

5f6d_7c89

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Transducin Heterotrimeric G protein in the visual cascade Rhodopsin Light-activated GPCR in rod photoreceptors cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_863c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons CNG channel (rod outer segment) Rod channel controlled by cGMP levels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Golf G protein coupling olfactory receptors to cAMP signaling Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_2db2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin Taste G protein used in bitter and sweet pathways Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Signaling molecule that helps open olfactory CNG channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins CNG channel (rod outer segment) Rod channel controlled by cGMP levels MAT

5f6d_a730

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Golf Heterotrimeric G protein used in olfactory GPCR pathways CNG channel (rod outer segment) Rod channel controlled by cGMP levels IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_bec1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation cGMP Cyclic nucleotide that gates rod outer segment ion channels Gustducin Taste G protein used in bitter and sweet pathways Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger MAT

5f6d_ec24

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Gustducin G protein that couples taste GPCRs to downstream second messengers Golf Olfactory G protein that activates adenylyl cyclase CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Rhodopsin Light-activated GPCR in rod photoreceptors Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance cGMP Signaling nucleotide that falls in light, closing CNG channels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_e49e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cGMP Second messenger that keeps rod CNG channels open in the dark IP3 Second messenger that triggers Ca2+ release from ER stores Gustducin Taste G protein used in bitter and sweet pathways Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_66b8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Signaling molecule that helps open olfactory CNG channels Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Golf Olfactory G protein that activates adenylyl cyclase CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_a26e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Gustducin G protein that couples taste GPCRs to downstream second messengers Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Transducin Heterotrimeric G protein in the visual cascade Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_5f3c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Golf Olfactory G protein that activates adenylyl cyclase cGMP Cyclic nucleotide that gates rod outer segment ion channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_2cec

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_5501

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs CNG channel (rod outer segment) Rod channel controlled by cGMP levels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Light-activated GPCR in rod photoreceptors Transducin Heterotrimeric G protein in the visual cascade Golf Heterotrimeric G protein used in olfactory GPCR pathways MAT

5f6d_4b48

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Ion channel involved in taste transduction downstream of IP3 Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Transducin Heterotrimeric G protein in the visual cascade IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_e315

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Heterotrimeric G protein used in olfactory GPCR pathways TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_ff89

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Rhodopsin Photopigment that starts rod phototransduction Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_365b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Transducin Heterotrimeric G protein in the visual cascade TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light MAT

5f6d_7843

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Transducin G protein that activates PDE6 in rod phototransduction CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons cAMP Cytosolic second messenger produced downstream of olfactory GPCRs TRPM5 Ion channel involved in taste transduction downstream of IP3 Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_4bf1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons cGMP Second messenger that keeps rod CNG channels open in the dark Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_5d52

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (rod outer segment) Rod channel controlled by cGMP levels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Transducin G protein that activates PDE6 in rod phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Second messenger that triggers Ca2+ release from ER stores Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_8c71

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cAMP Signaling molecule that helps open olfactory CNG channels Transducin Rod G protein linking rhodopsin to cGMP breakdown Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_8f42

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Transducin G protein that activates PDE6 in rod phototransduction cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Golf G protein coupling olfactory receptors to cAMP signaling Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_98c2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cGMP Second messenger that keeps rod CNG channels open in the dark Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Gustducin Heterotrimeric G protein in taste receptor signaling Transducin G protein that activates PDE6 in rod phototransduction Rhodopsin Photopigment that starts rod phototransduction Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_2400

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Gustducin Taste G protein used in bitter and sweet pathways IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells cGMP Signaling nucleotide that falls in light, closing CNG channels Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_03c2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin G protein that activates PDE6 in rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores cGMP Second messenger that keeps rod CNG channels open in the dark Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_8cc2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons cAMP Second messenger made from ATP that rises during odor detection Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_ba2c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Gustducin Heterotrimeric G protein in taste receptor signaling IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_8ab6

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_a1d4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin Taste G protein used in bitter and sweet pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_8f85

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin Taste G protein used in bitter and sweet pathways Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cGMP Signaling nucleotide that falls in light, closing CNG channels Rhodopsin Photopigment that starts rod phototransduction CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_83a1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction cGMP Signaling nucleotide that falls in light, closing CNG channels Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Photopigment that starts rod phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_9e13

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Signaling nucleotide that falls in light, closing CNG channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Transducin Rod G protein linking rhodopsin to cGMP breakdown CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Gustducin Taste G protein used in bitter and sweet pathways Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_9f78

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Rhodopsin Photopigment that starts rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores TRPM5 Ion channel involved in taste transduction downstream of IP3 Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light MAT

5f6d_d23a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Transducin Rod G protein linking rhodopsin to cGMP breakdown IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_f2b4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Golf G protein coupling olfactory receptors to cAMP signaling Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Ion channel involved in taste transduction downstream of IP3 Transducin G protein that activates PDE6 in rod phototransduction Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_d6dd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Second messenger made from ATP that rises during odor detection Golf Heterotrimeric G protein used in olfactory GPCR pathways TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Photopigment that starts rod phototransduction Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_1c96

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Signaling nucleotide that falls in light, closing CNG channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Light-activated GPCR in rod photoreceptors Transducin Rod G protein linking rhodopsin to cGMP breakdown Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_b8f8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Golf Olfactory G protein that activates adenylyl cyclase CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells cGMP Cyclic nucleotide that gates rod outer segment ion channels MAT

5f6d_6cc5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Golf Heterotrimeric G protein used in olfactory GPCR pathways CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons MAT

5f6d_9533

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Transducin Heterotrimeric G protein in the visual cascade cAMP Second messenger made from ATP that rises during odor detection Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_19a5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Transducin Heterotrimeric G protein in the visual cascade Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection TRPM5 Ion channel involved in taste transduction downstream of IP3 IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_f3bd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger cGMP Second messenger that keeps rod CNG channels open in the dark Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_777e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger cAMP Signaling molecule that helps open olfactory CNG channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Gustducin Taste G protein used in bitter and sweet pathways Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_fe4f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod TRPM5 Ion channel involved in taste transduction downstream of IP3 Golf G protein coupling olfactory receptors to cAMP signaling cAMP Signaling molecule that helps open olfactory CNG channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_12e1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Transducin G protein that activates PDE6 in rod phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons cGMP Second messenger that keeps rod CNG channels open in the dark Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_6156

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Golf Olfactory G protein that activates adenylyl cyclase Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Gustducin Heterotrimeric G protein in taste receptor signaling MAT

5f6d_73f4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger MAT

5f6d_8a7e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cAMP Second messenger made from ATP that rises during odor detection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Golf G protein coupling olfactory receptors to cAMP signaling TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response IP3 Second messenger that triggers Ca2+ release from ER stores Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_1305

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin G protein that couples taste GPCRs to downstream second messengers cGMP Second messenger that keeps rod CNG channels open in the dark Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Golf Olfactory G protein that activates adenylyl cyclase Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_a47e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Transducin Rod G protein linking rhodopsin to cGMP breakdown Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_959b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Golf Heterotrimeric G protein used in olfactory GPCR pathways cGMP Signaling nucleotide that falls in light, closing CNG channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_859b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_dbc5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_c0c1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Rhodopsin Photopigment that starts rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin Heterotrimeric G protein in taste receptor signaling cGMP Cyclic nucleotide that gates rod outer segment ion channels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_580f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Golf Olfactory G protein that activates adenylyl cyclase cAMP Second messenger made from ATP that rises during odor detection Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_f535

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Transducin Heterotrimeric G protein in the visual cascade IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_fcfd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_d572

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance cAMP Signaling molecule that helps open olfactory CNG channels Rhodopsin Photopigment that starts rod phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_c0de

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Rhodopsin Photopigment that starts rod phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_2a9f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Second messenger made from ATP that rises during odor detection Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Transducin G protein that activates PDE6 in rod phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways MAT

5f6d_d3e4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Signaling molecule that helps open olfactory CNG channels Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Golf Heterotrimeric G protein used in olfactory GPCR pathways Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_fa6e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Signaling molecule that helps open olfactory CNG channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Transducin G protein that activates PDE6 in rod phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Golf Heterotrimeric G protein used in olfactory GPCR pathways Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_20b9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cGMP Signaling nucleotide that falls in light, closing CNG channels CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light MAT

5f6d_270e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Transducin G protein that activates PDE6 in rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_7d91

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Second messenger that triggers Ca2+ release from ER stores Golf G protein coupling olfactory receptors to cAMP signaling Gustducin Taste G protein used in bitter and sweet pathways Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 MAT

5f6d_ed71

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Golf Olfactory G protein that activates adenylyl cyclase Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin G protein that activates PDE6 in rod phototransduction IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells cGMP Signaling nucleotide that falls in light, closing CNG channels MAT

5f6d_a2fd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Rhodopsin Light-activated GPCR in rod photoreceptors CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Golf G protein coupling olfactory receptors to cAMP signaling IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_b027

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Rod G protein linking rhodopsin to cGMP breakdown Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin cAMP Signaling molecule that helps open olfactory CNG channels CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_9850

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers TRPM5 Ion channel involved in taste transduction downstream of IP3 IP3 Molecule that opens IP3 receptors on internal Ca2+ stores cAMP Signaling molecule that helps open olfactory CNG channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs MAT

5f6d_31a3

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin Heterotrimeric G protein in the visual cascade Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins cGMP Cyclic nucleotide that gates rod outer segment ion channels MAT

5f6d_9443

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Transducin Heterotrimeric G protein in the visual cascade Gustducin Taste G protein used in bitter and sweet pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_c71f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Gustducin G protein that couples taste GPCRs to downstream second messengers Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_3e55

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Rhodopsin Photopigment that starts rod phototransduction Transducin Heterotrimeric G protein in the visual cascade CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod cAMP Signaling molecule that helps open olfactory CNG channels Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Golf G protein coupling olfactory receptors to cAMP signaling Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_95be

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Rhodopsin Light-activated GPCR in rod photoreceptors Gustducin G protein that couples taste GPCRs to downstream second messengers Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_7d77

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cGMP Second messenger that keeps rod CNG channels open in the dark Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Transducin Rod G protein linking rhodopsin to cGMP breakdown Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_16fc

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Rod G protein linking rhodopsin to cGMP breakdown cAMP Second messenger made from ATP that rises during odor detection IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 MAT

5f6d_6c9a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Rod G protein linking rhodopsin to cGMP breakdown Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Gustducin Taste G protein used in bitter and sweet pathways Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_5f2a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Gustducin Heterotrimeric G protein in taste receptor signaling cAMP Signaling molecule that helps open olfactory CNG channels CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_37a8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Transducin G protein that activates PDE6 in rod phototransduction Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Golf G protein coupling olfactory receptors to cAMP signaling CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light TRPM5 Ion channel involved in taste transduction downstream of IP3 Gustducin Taste G protein used in bitter and sweet pathways cGMP Second messenger that keeps rod CNG channels open in the dark MAT

5f6d_19b9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons cAMP Signaling molecule that helps open olfactory CNG channels Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_0568

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Golf G protein coupling olfactory receptors to cAMP signaling Rhodopsin Photopigment that starts rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Transducin G protein that activates PDE6 in rod phototransduction MAT

5f6d_a81f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Transducin Heterotrimeric G protein in the visual cascade cGMP Second messenger that keeps rod CNG channels open in the dark Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_3910

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation cGMP Signaling nucleotide that falls in light, closing CNG channels CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Transducin Heterotrimeric G protein in the visual cascade Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger IP3 Second messenger that triggers Ca2+ release from ER stores Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_df33

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_0528

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cAMP Signaling molecule that helps open olfactory CNG channels Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Gustducin G protein that couples taste GPCRs to downstream second messengers Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_2aef

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Second messenger that keeps rod CNG channels open in the dark Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Rhodopsin Photopigment that starts rod phototransduction Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger TRPM5 Ion channel involved in taste transduction downstream of IP3 Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_df67

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin G protein that couples taste GPCRs to downstream second messengers Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cGMP Signaling nucleotide that falls in light, closing CNG channels Golf G protein coupling olfactory receptors to cAMP signaling TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_8803

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin Heterotrimeric G protein in the visual cascade Golf Heterotrimeric G protein used in olfactory GPCR pathways cGMP Cyclic nucleotide that gates rod outer segment ion channels Gustducin G protein that couples taste GPCRs to downstream second messengers IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_83f6

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection cAMP Signaling molecule that helps open olfactory CNG channels Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 MAT

5f6d_562b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction cGMP Signaling nucleotide that falls in light, closing CNG channels CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Rhodopsin Photopigment that starts rod phototransduction MAT

5f6d_2d95

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_07d5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light cAMP Signaling molecule that helps open olfactory CNG channels Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_0c5e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Gustducin Taste G protein used in bitter and sweet pathways Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_d2a6

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Gustducin Heterotrimeric G protein in taste receptor signaling Transducin G protein that activates PDE6 in rod phototransduction TRPM5 Ion channel involved in taste transduction downstream of IP3 Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection IP3 Molecule that opens IP3 receptors on internal Ca2+ stores MAT

5f6d_615a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Transducin Rod G protein linking rhodopsin to cGMP breakdown Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production cGMP Signaling nucleotide that falls in light, closing CNG channels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_2d2a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells cAMP Second messenger made from ATP that rises during odor detection Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_f127

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Golf G protein coupling olfactory receptors to cAMP signaling Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod cAMP Signaling molecule that helps open olfactory CNG channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_3355

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Second messenger made from ATP that rises during odor detection Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Gustducin Taste G protein used in bitter and sweet pathways Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (rod outer segment) Rod channel controlled by cGMP levels MAT

5f6d_f642

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction CNG channel (rod outer segment) Rod channel controlled by cGMP levels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Golf Heterotrimeric G protein used in olfactory GPCR pathways Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_1630

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Gustducin Taste G protein used in bitter and sweet pathways Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Rhodopsin Light-activated GPCR in rod photoreceptors CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons cAMP Second messenger made from ATP that rises during odor detection MAT

5f6d_15e7

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Gustducin G protein that couples taste GPCRs to downstream second messengers Golf Heterotrimeric G protein used in olfactory GPCR pathways Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_1763

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells TRPM5 Ion channel involved in taste transduction downstream of IP3 Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Rhodopsin Light-activated GPCR in rod photoreceptors Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Transducin G protein that activates PDE6 in rod phototransduction CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_a404

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Heterotrimeric G protein in taste receptor signaling Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Ion channel involved in taste transduction downstream of IP3 Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_032f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (rod outer segment) Rod channel controlled by cGMP levels Gustducin Taste G protein used in bitter and sweet pathways MAT

5f6d_0eca

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Transducin G protein that activates PDE6 in rod phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_27af

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Gustducin Taste G protein used in bitter and sweet pathways Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_2b22

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells cGMP Signaling nucleotide that falls in light, closing CNG channels Golf Heterotrimeric G protein used in olfactory GPCR pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection MAT

5f6d_2b6f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Transducin Heterotrimeric G protein in the visual cascade Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_c4a9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cAMP Signaling molecule that helps open olfactory CNG channels Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin Taste G protein used in bitter and sweet pathways Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_3fdd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin Heterotrimeric G protein in taste receptor signaling Golf G protein coupling olfactory receptors to cAMP signaling MAT

5f6d_de11

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Gustducin Heterotrimeric G protein in taste receptor signaling Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Transducin Rod G protein linking rhodopsin to cGMP breakdown Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs cGMP Signaling nucleotide that falls in light, closing CNG channels MAT

5f6d_f890

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cGMP Cyclic nucleotide that gates rod outer segment ion channels CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_d4f0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Golf Olfactory G protein that activates adenylyl cyclase Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_6f52

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Transducin G protein that activates PDE6 in rod phototransduction CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_5d4f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Gustducin G protein that couples taste GPCRs to downstream second messengers Golf G protein coupling olfactory receptors to cAMP signaling Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_92af

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Gustducin G protein that couples taste GPCRs to downstream second messengers Transducin Heterotrimeric G protein in the visual cascade TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_9f52

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Golf Heterotrimeric G protein used in olfactory GPCR pathways TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Transducin Rod G protein linking rhodopsin to cGMP breakdown Gustducin G protein that couples taste GPCRs to downstream second messengers IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_9859

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light cGMP Signaling nucleotide that falls in light, closing CNG channels Gustducin G protein that couples taste GPCRs to downstream second messengers Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf MAT

5f6d_0347

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Transducin G protein that activates PDE6 in rod phototransduction cGMP Second messenger that keeps rod CNG channels open in the dark TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_8733

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Transducin Rod G protein linking rhodopsin to cGMP breakdown Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_d121

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Ion channel involved in taste transduction downstream of IP3 Transducin Rod G protein linking rhodopsin to cGMP breakdown Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Gustducin Heterotrimeric G protein in taste receptor signaling CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons MAT

5f6d_d991

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin G protein that couples taste GPCRs to downstream second messengers Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cGMP Signaling nucleotide that falls in light, closing CNG channels Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Transducin G protein that activates PDE6 in rod phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_e7a8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cGMP Signaling nucleotide that falls in light, closing CNG channels Transducin Rod G protein linking rhodopsin to cGMP breakdown Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_bdef

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Gustducin G protein that couples taste GPCRs to downstream second messengers Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_8ab3

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf G protein coupling olfactory receptors to cAMP signaling Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Gustducin G protein that couples taste GPCRs to downstream second messengers IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_bb57

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels MAT

5f6d_aeae

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Gustducin Heterotrimeric G protein in taste receptor signaling IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Golf Olfactory G protein that activates adenylyl cyclase Transducin Heterotrimeric G protein in the visual cascade Rhodopsin Photopigment that starts rod phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_b6e2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Golf Olfactory G protein that activates adenylyl cyclase Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_4768

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cGMP Cyclic nucleotide that gates rod outer segment ion channels Golf Olfactory G protein that activates adenylyl cyclase Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_85b4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Golf Olfactory G protein that activates adenylyl cyclase TRPM5 Ion channel involved in taste transduction downstream of IP3 Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_15cd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Gustducin G protein that couples taste GPCRs to downstream second messengers cAMP Second messenger made from ATP that rises during odor detection MAT

5f6d_5277

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Cytosolic second messenger produced downstream of olfactory GPCRs CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_3f8e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cAMP Second messenger made from ATP that rises during odor detection Transducin Heterotrimeric G protein in the visual cascade TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Gustducin Heterotrimeric G protein in taste receptor signaling IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_5c8d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Second messenger that keeps rod CNG channels open in the dark Rhodopsin Photopigment that starts rod phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Golf Heterotrimeric G protein used in olfactory GPCR pathways Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin MAT

5f6d_5877

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels cAMP Second messenger made from ATP that rises during odor detection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_d1b5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes cGMP Cyclic nucleotide that gates rod outer segment ion channels Golf Olfactory G protein that activates adenylyl cyclase Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_395e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Gustducin G protein that couples taste GPCRs to downstream second messengers Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf G protein coupling olfactory receptors to cAMP signaling Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation cAMP Signaling molecule that helps open olfactory CNG channels MAT

5f6d_f03b

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Rhodopsin Photopigment that starts rod phototransduction Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Golf Heterotrimeric G protein used in olfactory GPCR pathways Gustducin Taste G protein used in bitter and sweet pathways Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_0c78

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf Olfactory G protein that activates adenylyl cyclase CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf cGMP Cyclic nucleotide that gates rod outer segment ion channels Gustducin Heterotrimeric G protein in taste receptor signaling Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_8a49

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Golf Heterotrimeric G protein used in olfactory GPCR pathways IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Gustducin G protein that couples taste GPCRs to downstream second messengers Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (rod outer segment) Rod channel controlled by cGMP levels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_8370

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Transducin Rod G protein linking rhodopsin to cGMP breakdown Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance MAT

5f6d_1c9a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells cAMP Signaling molecule that helps open olfactory CNG channels Gustducin Heterotrimeric G protein in taste receptor signaling Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels MAT

5f6d_78f1

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin TRPM5 Ion channel involved in taste transduction downstream of IP3 Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels Gustducin G protein that couples taste GPCRs to downstream second messengers CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_8f76

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Gustducin G protein that couples taste GPCRs to downstream second messengers Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Golf Olfactory G protein that activates adenylyl cyclase Rhodopsin Light-activated GPCR in rod photoreceptors MAT

5f6d_497f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells cGMP Second messenger that keeps rod CNG channels open in the dark IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Golf Heterotrimeric G protein used in olfactory GPCR pathways CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_fa2a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cGMP Second messenger that keeps rod CNG channels open in the dark Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Golf Olfactory G protein that activates adenylyl cyclase Transducin Heterotrimeric G protein in the visual cascade IP3 Second messenger that triggers Ca2+ release from ER stores Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_b2e4

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Golf G protein coupling olfactory receptors to cAMP signaling CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger cAMP Cytosolic second messenger produced downstream of olfactory GPCRs Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells MAT

5f6d_0694

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Golf G protein coupling olfactory receptors to cAMP signaling Transducin Rod G protein linking rhodopsin to cGMP breakdown IP3 Second messenger that triggers Ca2+ release from ER stores Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_009f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Rhodopsin Photopigment that starts rod phototransduction Golf G protein coupling olfactory receptors to cAMP signaling Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger MAT

5f6d_1878

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins cGMP Cyclic nucleotide that gates rod outer segment ion channels Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Rhodopsin Light-activated GPCR in rod photoreceptors Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores TRPM5 Ion channel involved in taste transduction downstream of IP3 Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_1fd9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Transducin G protein that activates PDE6 in rod phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Golf G protein coupling olfactory receptors to cAMP signaling cGMP Second messenger that keeps rod CNG channels open in the dark CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin IP3 Second messenger that triggers Ca2+ release from ER stores MAT

5f6d_b9a5

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Rhodopsin Light-activated GPCR in rod photoreceptors Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Transducin G protein that activates PDE6 in rod phototransduction Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response cAMP Cytosolic second messenger produced downstream of olfactory GPCRs MAT

5f6d_abef

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling Transducin Heterotrimeric G protein in the visual cascade Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons IP3 Second messenger that triggers Ca2+ release from ER stores cGMP Cyclic nucleotide that gates rod outer segment ion channels Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons MAT

5f6d_2b28

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Golf Heterotrimeric G protein used in olfactory GPCR pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Rhodopsin Photopigment that starts rod phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels MAT

5f6d_6ea0

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (rod outer segment) Rod channel controlled by cGMP levels Gustducin G protein that couples taste GPCRs to downstream second messengers Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Transducin Heterotrimeric G protein in the visual cascade TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells MAT

5f6d_3b05

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Transducin G protein that activates PDE6 in rod phototransduction Gustducin G protein that couples taste GPCRs to downstream second messengers Rhodopsin Photopigment that starts rod phototransduction cGMP Signaling nucleotide that falls in light, closing CNG channels Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_2cfc

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf Olfactory G protein that activates adenylyl cyclase cGMP Second messenger that keeps rod CNG channels open in the dark IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Transducin Heterotrimeric G protein in the visual cascade Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_954f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Gustducin Taste G protein used in bitter and sweet pathways Rhodopsin Photopigment that starts rod phototransduction Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_d2be

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin TRPM5 Ion channel involved in taste transduction downstream of IP3 CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection cGMP Second messenger that keeps rod CNG channels open in the dark Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Golf Olfactory G protein that activates adenylyl cyclase MAT

5f6d_9ccc

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins cGMP Second messenger that keeps rod CNG channels open in the dark Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Second messenger that triggers Ca2+ release from ER stores CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons MAT

5f6d_da5a

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Light-activated GPCR in rod photoreceptors Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Second messenger that triggers Ca2+ release from ER stores Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Gustducin G protein that couples taste GPCRs to downstream second messengers TRPM5 Ion channel involved in taste transduction downstream of IP3 cAMP Signaling molecule that helps open olfactory CNG channels MAT

5f6d_1b6e

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Golf Heterotrimeric G protein used in olfactory GPCR pathways Rhodopsin Photopigment that starts rod phototransduction IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells CNG channel (olfactory) Cyclic nucleotide gated channel that depolarizes olfactory neurons Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Gustducin G protein that couples taste GPCRs to downstream second messengers MAT

5f6d_fc55

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf TRPM5 Ion channel involved in taste transduction downstream of IP3 Rhodopsin Light-activated GPCR in rod photoreceptors Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling cGMP Second messenger that keeps rod CNG channels open in the dark MAT

5f6d_b8fd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction TRPM5 Ion channel involved in taste transduction downstream of IP3 IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells CNG channel (rod outer segment) Rod channel controlled by cGMP levels Golf Olfactory G protein that activates adenylyl cyclase Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling MAT

5f6d_eeaf

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

cGMP Cyclic nucleotide that gates rod outer segment ion channels TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Gustducin G protein that couples taste GPCRs to downstream second messengers Golf G protein coupling olfactory receptors to cAMP signaling Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Rhodopsin Photopigment that starts rod phototransduction Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction MAT

5f6d_5f23

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Rhodopsin Photopigment that starts rod phototransduction TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins MAT

5f6d_e46c

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) cGMP-degrading enzyme downstream of transducin Gustducin Heterotrimeric G protein in taste receptor signaling Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation cAMP Signaling molecule that helps open olfactory CNG channels Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Golf Heterotrimeric G protein used in olfactory GPCR pathways Transducin Rod G protein linking rhodopsin to cGMP breakdown MAT

5f6d_7f42

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Gustducin Taste G protein used in bitter and sweet pathways Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cGMP Second messenger that keeps rod CNG channels open in the dark Golf Olfactory G protein that activates adenylyl cyclase Transducin G protein that activates PDE6 in rod phototransduction Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels MAT

5f6d_cabd

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Transducin G protein that activates PDE6 in rod phototransduction Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Gustducin Heterotrimeric G protein in taste receptor signaling Rhodopsin Light-activated GPCR in rod photoreceptors Olfactory receptor (GPCR) GPCR that initiates olfactory signaling in sensory neurons Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response MAT

5f6d_d91f

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction Golf Olfactory G protein that activates adenylyl cyclase Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 cAMP Signaling molecule that helps open olfactory CNG channels Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes TRPM5 Channel that helps depolarize taste receptor cells after GPCR activation MAT

5f6d_2be2

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation Golf G protein coupling olfactory receptors to cAMP signaling IP3 Second messenger that triggers Ca2+ release from ER stores Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells CNG channel (olfactory) Ion channel opened by cyclic nucleotides during odor detection Gustducin G protein that couples taste GPCRs to downstream second messengers Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes MAT

5f6d_23d8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling CNG channel (olfactory) Allows Ca2+ entry that can amplify the olfactory response TRPM5 Ion channel involved in taste transduction downstream of IP3 Golf Heterotrimeric G protein used in olfactory GPCR pathways cGMP Cyclic nucleotide that gates rod outer segment ion channels Rhodopsin Light-activated GPCR in rod photoreceptors Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_86d8

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells cGMP Signaling nucleotide that falls in light, closing CNG channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Transducin G protein that activates PDE6 in rod phototransduction Gustducin Taste G protein used in bitter and sweet pathways Adenylyl cyclase (AC3) Enzyme that converts ATP to cAMP in olfactory neurons MAT

5f6d_2fd9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

TRPM5 Ion channel involved in taste transduction downstream of IP3 Adenylyl cyclase (AC3) Enzyme that produces cAMP as a second messenger cGMP Cyclic nucleotide that gates rod outer segment ion channels Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Rhodopsin Light-activated GPCR in rod photoreceptors Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 CNG channel (rod outer segment) Ion channel that closes when cGMP falls, hyperpolarizing the rod IP3 Diffusible messenger that raises cytosolic Ca2+ in taste cells MAT

5f6d_f23d

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Gustducin Taste G protein used in bitter and sweet pathways cGMP Second messenger that keeps rod CNG channels open in the dark Phospholipase C-β2 (PLC-β2) Enzyme that cleaves PIP2 to generate IP3 Transducin Rod G protein linking rhodopsin to cGMP breakdown Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Mechanotransduction channel (hair cell MET channel) Ion channel opened by stereocilia deflection in hearing and balance CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light MAT

5f6d_90a9

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Phospholipase C-β2 (PLC-β2) Enzyme that produces IP3 downstream of taste GPCRs TRPM5 Cation channel activated downstream of Ca2+ signaling in taste cells Gustducin Heterotrimeric G protein in taste receptor signaling IP3 Molecule that opens IP3 receptors on internal Ca2+ stores Mechanotransduction channel (hair cell MET channel) Mechanically gated channel that allows cation influx in hair cells Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production Rhodopsin Opsin plus retinal that activates transducin when retinal isomerizes Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection MAT

5f6d_5936

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

IP3 Second messenger that triggers Ca2+ release from ER stores Rhodopsin Light-activated GPCR in rod photoreceptors Phospholipase C-β2 (PLC-β2) PIP2-cleaving enzyme in bitter, sweet, and umami taste signaling Tip link (hair cell bundle) Mechanical tether that transmits force to open mechanotransduction channels Phosphodiesterase 6 (PDE6) Enzyme that lowers cGMP concentration during phototransduction CNG channel (rod outer segment) cGMP-gated channel that is open in darkness and closes in light Golf G protein coupling olfactory receptors to cAMP signaling Olfactory receptor (GPCR) Odorant-activated GPCR upstream of cAMP production MAT

5f6d_0456

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Golf G protein coupling olfactory receptors to cAMP signaling cGMP Cyclic nucleotide that gates rod outer segment ion channels Tip link (hair cell bundle) Structure whose tension changes during stereocilia deflection Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins TRPM5 Ion channel involved in taste transduction downstream of IP3 IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Rod channel controlled by cGMP levels Mechanotransduction channel (hair cell MET channel) Allows K+ influx from K+ rich endolymph to depolarize hair cells MAT

5f6d_3265

Match each of the following sensory transduction components with their corresponding functions in signaling.

Note: Each choice will be used exactly once.

Rhodopsin Photopigment that starts rod phototransduction Adenylyl cyclase (AC3) ATP-to-cAMP enzyme downstream of Golf Olfactory receptor (GPCR) Receptor that binds odorants and activates G proteins Golf Olfactory G protein that activates adenylyl cyclase Tip link (hair cell bundle) Link between stereocilia that helps gate transduction channels IP3 Molecule that opens IP3 receptors on internal Ca2+ stores CNG channel (rod outer segment) Rod channel controlled by cGMP levels Phosphodiesterase 6 (PDE6) Enzyme that hydrolyzes cGMP in rods after light activation