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Deletion mutants

Deduce the gene order from deletions

Deletion mutants are chromosomes with a chunk missing. Which genes still work, and which fail, tells you which genes sit inside the missing region. This puzzle uses that evidence to build a gene map, the classic way geneticists learned chromosome structure before genomes were cheap.

How to solve the deletion mutant puzzle

Your goal is to determine the linear order of the genes on a chromosome using deletion mutant evidence.

  1. Use the deletion list to see which genes are uncovered together.
  2. Use the table to identify which deletions overlap and which are nested.
  3. Fit the genes into a single consistent order that explains every deletion.
  4. Enter your gene order using each gene letter exactly once.