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1: Genetic Disorders

Students identify common genetic disorders and describe basic inheritance patterns associated with single-gene conditions.

LibreTexts reference: Chapter 1: Foundations of Genetic Disorders LibreTexts

Genetic Disorders and Descriptions

Click to show Genetic Disorders and Descriptions example problem

Match each of the following genetic disorders with their corresponding descriptions.
Note: Each choice will be used exactly once.

Your Choice Prompt
Drop Your Choice Here 1. Prader-Willi syndrome
Drop Your Choice Here 2. Hemophilia
Drop Your Choice Here 3. DiGeorge syndrome
Drop Your Choice Here 4. Achondroplasia
Drop Your Choice Here 5. Maple syrup urine disease

Drag one of the choices below:

  • A. an inherited bleeding disorder in which the blood does NOT clot properly
  • B. disorder that is due to a missing piece (deletion) of a specific part of chromosome 22
  • C. gets its name from the distinctive sweet odor of affected infants' urine
  • D. impairs the growth of bone in the limbs and causes abnormal growth in the spine and skull
  • E. a genetic disorder caused by a loss of function of specific genes on chromosome 15
 

Genetic Terminology and Definitions

Click to show Genetic Terminology and Definitions example problem

Match each of the following genetic terms with their corresponding definitions.
Note: Each choice will be used exactly once.

Your Choice Prompt
Drop Your Choice Here 1. genetics
Drop Your Choice Here 2. haploid
Drop Your Choice Here 3. diploid
Drop Your Choice Here 4. homologous chromosomes
Drop Your Choice Here 5. genomics

Drag one of the choices below:

  • A. two similar but different copies of a chromosome
  • B. the study of the effect of genetic differences on organisms
  • C. a cell or organism that a single set of chromosomes
  • D. the structure, function, evolution, and mapping of genomes
  • E. a cell or organism that has paired chromosomes
 

Genetic Disorders from Descriptions

Click to show Genetic Disorders from Descriptions example problem

Which one of the following genetic disorders correspond to the description 'autosomal recessive genetic disorder affecting most critically the lungs'.

 

Genetic Terminology from Definitions

Click to show Genetic Terminology from Definitions example problem

Which one of the following genetic terms correspond to the definition 'the unit of inheritance passed from parents to offspring'.

 

Metabolic Pathway Order from Nutrient Supplementation (4 Metabolites)

Click to show Metabolic Pathway Order from Nutrient Supplementation (4 Metabolites) example problem
enzyme 1 enzyme 2 enzyme 3
D E H N

Look at the metabolic pathway in the table above.
Metabolite N is needed for the bacteria to grow.
Consider a bacterial strain that is mutant for the gene coding for enzyme 2
Which nutrients, when added to minimal media, will help this bacteria grow?
Multiple answers may be correct.

 

Metabolic Pathway Order from Nutrient Supplementation (6 Metabolites)

Click to show Metabolic Pathway Order from Nutrient Supplementation (6 Metabolites) example problem
enzyme 1 enzyme 2 enzyme 3 enzyme 4 enzyme 5
C D E K P X

Look at the metabolic pathway in the table above.
Metabolite X is needed for the bacteria to grow.
Consider a bacterial strain that is mutant for the gene coding for enzyme 3
Which nutrients, when added to minimal media, will help this bacteria grow?
Multiple answers may be correct.

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