5: Medicinal Biotechnology
Students assess gene therapy, viral vectors, genome editing (ZFNs, TALENs, CRISPR), stem cells, iPSC therapies, CAR-T therapy, cancer gene therapy, and prime editing.
Matching Genetic Disease Treatment Methods to Descriptions
Click to show Matching Genetic Disease Treatment Methods to Descriptions example problem
Match each of the following genetic disease treatment methods with their corresponding descriptions.
Note: Each choice will be used exactly once.
| Your Choice | Prompt | |
|---|---|---|
| 1. gene therapy | ||
| 2. genome editing |
Drag one of the choices below:
- A. introducing a new gene on a plasmid into a patient to replace a faulty β-thalassemia enzyme
- B. using CRISPR to change a single nucleotide in sickle-cell allele
Matching Stem Cell Potency Levels to Definitions
Click to show Matching Stem Cell Potency Levels to Definitions example problem
Match each of the following potencies of stem cells with their corresponding descriptions.
Note: Each choice will be used exactly once.
| Your Choice | Prompt | |
|---|---|---|
| 1. totipotent | ||
| 2. multipotent | ||
| 3. unipotent | ||
| 4. oligopotent | ||
| 5. pluripotent |
Drag one of the choices below:
- A. have the ability to transform into a small number of types of cells; e.g., plasma cells
- B. they are found in most body organs, where they replace diseased or aged cells
- C. in comparison with other types of stem cells, this type has the lowest differentiation potential
- D. can differentiate into all three basic body layers; e.g., embryonic stem cells
- E. can give rise to any of the 220 cell types found in an embryo as well as extra-embryonic cells (placenta)
Genetic Disease Treatment Methods from Descriptions
Click to show Genetic Disease Treatment Methods from Descriptions example problem
Which one of the following genetic disease treatment methods correspond to the description 'using CRISPR to change a single nucleotide in sickle-cell allele'.
Stem Cell Potency Levels from Definitions
Click to show Stem Cell Potency Levels from Definitions example problem
Which one of the following potencies of stem cells correspond to the description 'the capacity to develop into only one type of cell or tissue; e.g., epidermal stem cells'.