5: Medicinal Biotechnology
Students assess gene therapy, viral vectors, genome editing (ZFNs, TALENs, CRISPR), stem cells, iPSC therapies, CAR-T therapy, cancer gene therapy, and prime editing.
Matching Genetic Disease Treatment Methods to Descriptions
Click to show Matching Genetic Disease Treatment Methods to Descriptions example problem
Match each of the following genetic disease treatment methods with their corresponding descriptions.
Note: Each choice will be used exactly once.
| Your Choice | Prompt | |
|---|---|---|
| 1. genome editing | ||
| 2. gene therapy |
Drag one of the choices below:
- A. using zinc finger nuclease (ZFN) mediated treatment to replace a nucleotide in the diseased β-thalassemia allele
- B. culture and reprogram blood progenitor cells from bone marrow to kill HIV-infected cells
Matching Stem Cell Potency Levels to Definitions
Click to show Matching Stem Cell Potency Levels to Definitions example problem
Match each of the following potencies of stem cells with their corresponding descriptions.
Note: Each choice will be used exactly once.
| Your Choice | Prompt | |
|---|---|---|
| 1. oligopotent | ||
| 2. pluripotent | ||
| 3. multipotent | ||
| 4. totipotent | ||
| 5. unipotent |
Drag one of the choices below:
- A. myeloid stem cells are this type because they only produce a few types of cells; e.g., neutrophils and eosinophils
- B. can differentiate into all of the cell types of the body as well as placental cells; e.g., first two zygote cells after fertilization
- C. derived from the mesoderm, they are widely found throughout the body and can be easily isolated and cultured
- D. cells that can maintain an undifferentiated state indefinitely and can differentiate into most, if NOT all, cells of the body
- E. can differentiate into only one type of cell; e.g., skin cells
Genetic Disease Treatment Methods from Descriptions
Click to show Genetic Disease Treatment Methods from Descriptions example problem
Which one of the following genetic disease treatment methods correspond to the description 'deleting the fragments of HIV DNA from the genome of an infected patient'.
Stem Cell Potency Levels from Definitions
Click to show Stem Cell Potency Levels from Definitions example problem
Which one of the following potencies of stem cells correspond to the description 'they are found in most body organs, where they replace diseased or aged cells'.